Variability of quantal synaptic currents in thalamocortical neurons
نویسندگان
چکیده
منابع مشابه
Variability of quantal synaptic currents in thalamocortical neurons.
Broad amplitude variability and skewed distributions are characteristic features of quantal synaptic currents (minis) at central synapses. The relative contributions of the various underlying sources are still debated. Through computational models of thalamocortical neurons, we separated intra- from extra-synaptic sources. Our simulations indicate that the external factors of local input resist...
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In brain slice preparations of thalamocortical neurons with TTX, APV, CNQX, DNQX, and cesium present, spontaneous miniature inhibitory postsynaptic current (GABA mIPSCs) amplitudes are widely varying (5-80pA), with a skewed distribution. In computational models of reconstructed thalamocortical neurons, with the same currents blocked but without intra-synaptic variables, mIPSC amplitudes are nar...
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ژورنال
عنوان ژورنال: Thalamus and Related Systems
سال: 2003
ISSN: 1472-9288,1744-8107
DOI: 10.1017/s1472928803000086